Lori was born in Toledo, OH and received her BFA in Acting from Wright State University. Right out of college, she toured the country as a singer in a Top 40 cover band, and moved to Chicago soon after.
She is an alumn of the National Touring Company of The Second City, and was honored to perform with them in Iraq and Kuwait as part of a USO Tour in 2004. She works with Second City's Business Communications and Theatricals divisions, both as a performer and workshop facilitator, and toured with their musical, “Sex and the Second City.”
She understudied for the Second City Mainstage and ETC shows and completed a summer-long run of the ETC show, “Immaculate Deception” in 2007. She is a founding member of The WNEP Theater Foundation, with whom she wrote and performed in many productions; most notably, a musical entitled “The Wicked and the Sexed” (New City's 1997 Best Original Musical Production).
You may also have seen her improvise with the all-female group, “Sirens,” “ComedySportz” and in their productions “Blind Date,” “Whose Chorus Line Is It Anyway?” (director) and “Trois'.” One of her favorite scripted roles was Xena Warrior Princess in “Xena Live!” Lori can also be heard as the vocalist for the Chicago jazz group, the “Lori McClain Trio.”
She has been an artist-in-residence at the University of Chicago Lab School summer drama program since 2005, and currently teaches and coaches numerous improv groups in and around Chicago.
She can be seen in television commercials for “Meijer’s Stores,” “Aldi,” “Walmart,” and “Lyrica," and "KFC," and is the voice of Shiva in the “Mortal Kombat” video game series, as well acting for several voice-overs and book narrations.
She created the role of Patti Blagojevich in Second City’s, “Rod Blagojevich Superstar!” and joyously portrayed fictional corporate country singer and alcohol enthusiast, Missy Brisco, in “Lanyard Skynerd, The Musical!” at Martyr’s Live in Chicago. In 2017, Lori portrayed First Daughter, Martha Jefferson in "Monticello" for Aurora Theatre works in Chicago.